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Ten-eleven-translocation (TET) protein

" in MedChemExpress (MCE) Product Catalog:

46

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8

Fluorescent Dye

4

Peptides

2

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2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-122258
    NSC-370284

    		STAT TET Protein Cancer
    NSC-370284 is a selective inhibitor of ten-eleven translocation 1 (TET1) and 5-hydroxymethylcytosine (5hmC). NSC-370284 significantly inhibits the level of TET1 expression via targets STAT3/5 .
    NSC-370284
  • HY-P3459A
    Tet-213 TFA

    		Bacterial Infection
    Tet-213 TFA is a antimicrobial peptide. Tet-213 TFA has broad spectrum antibacterial activity. Tet-213 TFA can promote infected wound repair .
    <em>Tet</em>-213 TFA
  • HY-W396714
    Succinic acid sodium

    Wormwood acid sodium

    		 Potassium Channel TET Protein Neurological Disease
    Succinic acid sodium is a potent and orally active anxiolytic agent. Succinic acid sodium shows inhibitory effects on colonic epithelial cell proliferation in vivo. Succinic acid sodium can down-regulate the expression of KCNMB1 (potassium channel subunit β1) and TET1 (ten‑eleven translocation 1). Succinic acid sodium can be used for gestational hypertension research .
    Succinic acid sodium
  • HY-P3459
    Tet-213

    		Bacterial Infection
    Tet-213 is a antimicrobial peptide. Tet-213 has broad spectrum antibacterial activity. Tet-213 can promote infected wound repair .
    <em>Tet</em>-213
  • HY-P5486
    Tet-20

    		Bacterial Others
    Tet-20 is a biological active peptide. (Tet-20, is a synthetic cathelicidin-derived peptide. It was tested as infection-resistant coating for medical devices. When tethered on an implant surface Tet-20 exhibited broad antimicrobial activities both in vivo and in vitro. It can stop biofilm formation and appears to be non-toxic to eukaryotic cells)
    <em>Tet</em>-20
  • HY-D1898
    6-TET Azide

    		Fluorescent Dye Others
    6-TET Azide is a fluorescent probe that can be used for the preparation of fluorescent contrast agent and nucleic acid sequencing .
    6-<em>TET</em> Azide
  • HY-D1897
    6-TET phosphoramidite

    5′-Tetrachlorofluorescein phosphoramidite

    		 Fluorescent Dye Others
    6-TET phosphoramidite (5′-Tetrachlorofluorescein phosphoramidite) is a fluorescent dye that can be used for labeling an oligonucleotide with fluorescein .
    6-<em>TET</em> phosphoramidite
  • HY-D2116
    TAMRA-PEG8-Me-Tet

    		Fluorescent Dye Others
    TAMRA-PEG8-Me-Tet 是含有 8 个 PEG 单元的 TAMRA (HY-135640) 染料衍生物。TAMRA-PEG8-Me-Tet 含有 Tetrazine 基团，可以和含有 TCO 基团的分子发生逆电子需求 Diels-Alder 反应 (iEDDA)。
    TAMRA-PEG8-Me-<em>Tet</em>
  • HY-156313
    Me-Tet-PEG4-NHS

    		ADC Linker Cancer
    Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG4-NHS
  • HY-156475
    Me-Tet-PEG2-COOH

    		ADC Linker Cancer
    Me-Tet-PEG2-COOH is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-COOH can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG2-COOH
  • HY-156476
    Me-Tet-PEG2-NHS

    		ADC Linker Cancer
    Me-Tet-PEG2-NHS is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG2-NHS
  • HY-156477
    Me-Tet-PEG8-NHBoc

    		ADC Linker Cancer
    Me-Tet-PEG8-NHBoc is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG8-NHBoc
  • HY-156478
    Me-Tet-PEG4-NHBoc

    		ADC Linker Cancer
    Me-Tet-PEG4-NHBoc is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG4-NHBoc
  • HY-156479
    Me-Tet-PEG3-NHBoc

    		ADC Linker Cancer
    Me-Tet-PEG3-NHBoc is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG3-NHBoc
  • HY-156490
    Me-Tet-PEG5-NHS

    		ADC Linker Cancer
    Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG5-NHS
  • HY-156491
    Me-Tet-PEG9-NHS

    		ADC Linker Cancer
    Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG9-NHS
  • HY-156492
    Me-Tet-PEG4-COOH

    		ADC Linker Cancer
    Me-Tet-PEG4-COOH is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG4-COOH
  • HY-156493
    Me-Tet-PEG5-COOH

    		ADC Linker Cancer
    Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG5-COOH
  • HY-156494
    Me-Tet-PEG9-COOH

    		ADC Linker Cancer
    Me-Tet-PEG9-COOH is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG9-COOH
  • HY-156495
    Biotin-PEG3-Me-Tet

    		ADC Linker Cancer
    Biotin-PEG3-Me-Tet is an ADC Linker containing 3 PEG units. Biotin-PEG3-Me-Tet can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Biotin-PEG3-Me-<em>Tet</em>
  • HY-RS14384
    TET1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TET1 Human Pre-designed siRNA Set A contains three designed siRNAs for TET1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TET1 Human Pre-designed siRNA Set A
    TET1 Human Pre-designed siRNA Set A
  • HY-RS14385
    TET2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TET2 Human Pre-designed siRNA Set A contains three designed siRNAs for TET2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TET2 Human Pre-designed siRNA Set A
    TET2 Human Pre-designed siRNA Set A
  • HY-RS14386
    TET3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TET3 Human Pre-designed siRNA Set A contains three designed siRNAs for TET3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TET3 Human Pre-designed siRNA Set A
    TET3 Human Pre-designed siRNA Set A
  • HY-D2118
    TAMRA-PEG3-Me-Tet

    		Fluorescent Dye Others
    TAMRA-PEG3-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    TAMRA-PEG3-Me-<em>Tet</em>
  • HY-D2117
    TAMRA-PEG4-Me-Tet

    		Fluorescent Dye Others
    TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    TAMRA-PEG4-Me-<em>Tet</em>
  • HY-156300
    Me-Tet-PEG4-NH2

    		ADC Linker Cancer
    Me-Tet-PEG4-NH2 is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG4-NH2
  • HY-156301A
    Me-Tet-PEG8-NH2 hydrochloride

    		ADC Linker Cancer
    Me-Tet-PEG8-NH2 (hydrochloride) is an ADC Linker containing 2 PEG units. Me-Tet-PEG8-NH2 (hydrochloride) can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG8-NH2 hydrochloride
  • HY-W591272
    Me-Tet-PEG3-NH2

    		ADC Linker Cancer
    Me-Tet-PEG3-NH2 is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
    Me-<em>Tet</em>-PEG3-NH2
  • HY-156307
    Me-Tet-PEG3-Maleimide

    		ADC Linker Cancer
    Me-Tet-PEG3-Maleimide is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
    Me-<em>Tet</em>-PEG3-Maleimide
  • HY-156308
    Me-Tet-PEG4-Maleimide

    		ADC Linker Cancer
    Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
    Me-<em>Tet</em>-PEG4-Maleimide
  • HY-156312
    Me-Tet-PEG8-Maleimide

    		ADC Linker Cancer
    Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
    Me-<em>Tet</em>-PEG8-Maleimide
  • HY-155498
    TETS-4-Methylaniline

    		GABA Receptor Neurological Disease
    TETS-4-Methylaniline (compound 2k) is a hapten. TETS-4-Methylaniline conjugates to the carrier protein via using either diazotization or glutaraldehyde methods .
    TETS-4-Methylaniline
  • HY-161006
    (S)-TETS-C4-acid

    		Others Inflammation/Immunology
    (S)-TETS-C4-acid (Compound 2d) is a hapten coupled directly to a carrier protein through a carboxylic acid functionality. (S)-TETS-C4-acid (Compound 2d) can be used to detect tetramethylenedisulfotetramine (TETS) .
    (S)-TETS-C4-acid
  • HY-111558A
    Bobcat339 hydrochloride
    Maximum Cited Publications
    14 Publications Verification

    		 DNA Methyltransferase TET Protein Cancer
    Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme, with the IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 hydrochloride is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription .
    Bobcat339 hydrochloride
  • HY-111558
    Bobcat339
    Maximum Cited Publications
    14 Publications Verification

    		 DNA Methyltransferase TET Protein Cancer
    Bobcat339 is a potent and selective cytosine-based inhibitor of TET enzyme, with IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription .
    Bobcat339
  • HY-120395
    UC-514321

    		STAT Apoptosis TET Protein Inflammation/Immunology Cancer
    UC-514321, a structural analog of NSC370284 with higher activity, directly targets STAT3/5 and represses TET1 expression, but not TET2 or TET3. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity .
    UC-514321
  • HY-D0828
    3,6-Dichlorotrimellitic acid

    		DNA Stain Others
    3,6-Dichlorotrimellitic acid is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.
    3,6-Dichlorotrimellitic acid
  • HY-D0829
    3,6-Dichlorotrimellitic anhydride

    		DNA Stain Others
    3,6-Dichlorotrimellitic anhydride is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.
    3,6-Dichlorotrimellitic anhydride
  • HY-161005
    TETS-Methyl benzoate

    		Others Metabolic Disease
    TETS-Methyl benzoate(compound 2j) is a haptendirectly conjugated to the carrier protein via carboxylic acid function using the standard activated ester method .
    TETS-Methyl benzoate
  • HY-113038B
    α-Hydroxyglutaric acid

    2-Hydroxyglutarate; 2-Hydroxyglutaric acid; 2-Hydroxypentanedioic acid

    		 Histone Demethylase Endogenous Metabolite Cancer
    α-Hydroxyglutaric acid (2-Hydroxyglutarate) is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
    α-Hydroxyglutaric acid
  • HY-113038A
    α-Hydroxyglutaric acid disodium

    2-Hydroxyglutarate disodium; 2-Hydroxyglutaric acid disodium; 2-Hydroxypentanedioic acid disodium

    		 Histone Demethylase Endogenous Metabolite Cancer
    α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
    α-Hydroxyglutaric acid disodium
  • HY-129079A
    TFMB-(S)-2-HG
    1 Publications Verification

    		 DNA Methyltransferase Cancer
    TFMB-(S)-2-HG is a potent inhibitor of the 5'-methylcytosine hydroxylase TET2. TFMB-(S)-2-HG also inhibits the EglN prolyl hydroxylases. TFMB-(S)-2-HG has the potential for the research of acute myeloid leukemia (AML) .
    TFMB-(S)-2-HG
  • HY-148182
    TP-6076

    		Antibiotic Bacterial Parasite Infection
    TP-6076 is a fully synthetic fluorocycline antibiotic, acts function via binding to the 30S ribosomal subunit and maintains its activity. TP-6076 displays potent mechanism-based antitranslational activity (Tet protein, IC50=0.18 μg/mL), shows a wide range of antimicrobial and antiparasitic activities .
    TP-6076
  • HY-113038AS
    α-Hydroxyglutaric acid-13C5 disodium

    2-Hydroxyglutarate-13C5 disodium; 2-Hydroxyglutaric acid-13C5 sodium; 2-Hydroxypentanedioic acid-13C5 disodium

    		 Histone Demethylase Endogenous Metabolite Cancer
    α-Hydroxyglutaric acid- 13C5 (sodium) is the 13C labeled α-Hydroxyglutaric acid sodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) sodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid sodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2].
    α-Hydroxyglutaric acid-13C5 disodium
  • HY-113038AS1
    α-Hydroxyglutaric acid-d4 disodium

    2-Hydroxyglutarate-d4 disodium; 2-Hydroxyglutaric acid-d4 disodium; 2-Hydroxypentanedioic acid-d4 disodium

    		 Histone Demethylase Endogenous Metabolite Cancer
    α-Hydroxyglutaric acid-d4 (disodium) is the deuterium labeled α-Hydroxyglutaric acid disodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2].
    α-Hydroxyglutaric acid-d4 disodium
  • HY-12303
    OAC1
    1 Publications Verification

    		 Oct3/4 TET Protein Cancer
    OAC1 is a potent Oct4 activator. OAC1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. OAC1 activates OCT4 through upregulation of HOXB4 expression. OAC1 increases transcription of the Oct4-Nanog-Sox2 triad and TET1. OAC1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time .
    OAC1

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